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Amiodarone and Thyroid Toxicity

Many people who have certain heart rhythm problems may benefit from using amiodarone (Cordarone®, Pacerone®, Nexterone®). However, this medication may increase the risk for serious complications. Before starting amiodarone, make sure to let your healthcare provider know if you have any medical problems, such as thyroid problems.
 
Amiodarone can cause thyroid toxicity, which may lead to an underactive or overactive thyroid (hypothyroidism or hyperthyroidism, respectively). Your healthcare provider will check your thyroid function using a blood test before and periodically during treatment. Contact your healthcare provider immediately if you develop signs of thyroid problems, such as:
 
  • Weakness
  • Unexplained weight loss or weight gain
  • Sweating
  • Problems concentrating.
 
(For more information, click Precautions and Warnings With Amiodarone. This full-length article takes an in-depth look at other important safety concerns to review before starting treatment, including a list of who should not use this medication.)
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Last reviewed by: Kristi Monson, PharmD
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