Amiodarone for Atrial Fibrillation

Amiodarone (Cordarone®, Pacerone®, Nexterone®) is a prescription medication used to treat life-threatening arrhythmias known as ventricular fibrillation and ventricular tachycardia.
However, there may be times when a healthcare provider prescribes this medicine for "off-label," or unapproved, uses. For example, using amiodarone for atrial fibrillation is considered one off-label use of this medication.
As a Class III antiarrhythmic medication, amiodarone works by blocking potassium channels in the heart, preventing potassium from leaving the cells of the heart muscle. This action prolongs the time that the heart will respond to a new electrical signal. This helps prevent the heart from receiving a premature signal that is trying to tell the heart to beat too soon.
(For more details, click What Is Amiodarone Used For?. This Web page presents a closer look at specific uses for amiodarone, including how the drug works, approved uses, and when a healthcare provider may prescribe it for unapproved reasons.)
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