Drug Interactions With Amiodarone

More Detail on Drug Interactions With Amiodarone

The following sections explain in detail the potentially negative interactions that can occur when amiodarone is combined with any of the drugs listed above.
 
Azithromycin
Combining Amiodarone with azithromycin may increase the risk for potentially serious heart rhythm problems. If you must use these medicines together, your healthcare provider will need to closely monitor you.
 
Beta Blockers
Amiodarone should be used with caution in people taking a beta blocker medicine due to the risk for a dangerously low heart rate. Your healthcare provider will need to closely monitor you if you use these medicines together. However, this interaction is not likely to occur with beta blocker eye drops.
 
Bile Acid Sequestrants
Bile acid sequestrants may bind to amiodarone in the gastrointestinal (GI) tract, and decrease the amount of medicine absorbed into the bloodstream. This could make amiodarone less effective. In general, these medicines should not be used together unless absolutely necessary.
 
Certain Statin Medications
Amiodarone can increase the blood levels of certain statin medications. If you take a statin with amiodarone, your healthcare provider may need to give you a lower statin dose or choose one that does not interact with amiodarone.
 
Cimetidine
Cimetidine has been reported to increase amiodarone blood levels. It is probably best to avoid taking these medications together. If you need a medication for heartburn or sour stomach while taking amiodarone, your healthcare provider can help you choose one that is not likely to interact with amiodarone.
 
Clopidogrel
Amiodarone can make clopidogrel less effective. Talk to your healthcare provider about this potential interaction before taking these medicines together.
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