Cordarone Drug Interactions

Cordarone Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Cordarone is combined with any of the drugs listed above.
Combining Cordarone with azithromycin may increase the risk for potentially serious heart rhythm problems. If you must use these medicines together, your healthcare provider will need to closely monitor you.
Beta Blockers
Cordarone should be used cautiously in people taking a beta blocker medicine, because of the risk for a dangerously low heart rate. Your healthcare provider will need to closely monitor you if you take these medicines together. However, this interaction is not likely to occur with beta blocker eye drops.
Bile Acid Sequestrants
Bile acid sequestrants may bind to Cordarone in the gastrointestinal (GI) tract, and decrease the amount of the medicine absorbed into the bloodstream. This could make Cordarone less effective. In general, these medicines should not be used together unless absolutely necessary.
Certain Statin Medications
Cordarone can increase the blood levels of certain statin medications. If you take a statin with Cordarone, your healthcare provider may need to give you a lower statin dose or choose one that does not interact with Cordarone.
Cimetidine has been reported to increase Cordarone blood levels. It is probably best to avoid taking these medications together. If you need a medication for heartburn or sour stomach while taking Cordarone, your healthcare provider can help you choose one that is not likely to interact with Cordarone.
Cordarone can make clopidogrel less effective. Talk to your healthcare provider about this potential interaction before taking these medicines together.
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Cordarone Drug Information

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