Disopyramide and Breastfeeding

Although the manufacturer of disopyramide recommends that women not use this drug while nursing, many experts consider it safe for use while breastfeeding. Disopyramide has been shown to pass through breast milk. Although no problems have been reported in cases where women used the drug while nursing, disopyramide is associated with potentially serious risks that should be discussed with your healthcare provider.

Can Breastfeeding Women Take Disopyramide?

Disopyramide (Norpace®, Norpace® CR) is a prescription medication used to treat people with certain type of serious abnormal heartbeats. It belongs to a group of medications known as antiarrhythmics. This medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, you should discuss this with your healthcare provider before taking disopyramide.

More Information About Disopyramide and Breastfeeding

There have been several reports describing the use of disopyramide by breastfeeding women. In these reports, the drug was shown to pass through breast milk; however, no problems were observed in the nursing infants. Based on the amount of the medication found in the breast milk, researchers have estimated that a nursing infant would receive approximately 1.3 percent to 8 percent of the mother's daily disopyramide dosage.
The manufacturer recommends that women not use disopyramide while breastfeeding due to the potential for serious side effects in a nursing child. However, other experts, including the American Academy of Pediatrics (AAP), generally consider disopyramide safe for use during breastfeeding, especially if safer medications are not an option.
If your healthcare provider recommends this medication while you are nursing, make sure to closely observe your infant for any potential disopyramide side effects, such as:
  • Constipation
  • A change in the amount your child urinates
  • Dry eyes, nose, or mouth
  • Restlessness.
Let your child's healthcare provider know if you notice any of these symptoms, or anything else that seems out of the ordinary for your child.
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Disopyramide Drug Information

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