How Does It Work?

Disopyramide belongs to a group of medications known as Class I antiarrhythmics. Class I antiarrhythmic medications block sodium channels in the heart. This slows down the speed at which electrical impulses move through the heart, which helps stabilize the heart rhythm.
Disopyramide also extends the period of time that heart cells will not respond to a new electrical signal. This helps the heart tissue resist an electrical signal that is trying to come through too soon.

When and How to Take This Medication

Some general considerations to keep in mind during treatment with disopyramide include the following:
  • This medication comes in the form of a capsule. It is usually taken by mouth every 6 or 12 hours, depending on the particular product being taken.
  • You will start treatment in a hospital, where a healthcare provider can closely monitor you.
  • Disopyramide can be taken with or without food. Try taking it with food if it seems to bother your stomach.
  • The capsules should be swallowed whole; do not crush or chew them.
  • Immediate-release disopyramide can be made into a liquid suspension. Ask your pharmacist about this option if you have difficulty swallowing the capsules.
  • You should try to take your doses at the same times each day to keep an even level of the drug in your bloodstream.
  • For the medication to work properly, it must be taken as prescribed. Do not stop taking disopyramide, even if you feel well, as your irregular heartbeat may return.

Dosing Information for Disopyramide

The dose of disopyramide your healthcare provider recommends will vary, depending on a number of factors, including:
  • How you respond to the medication
  • Your weight
  • Your age
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Disopyramide Dosage for more information.)
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Disopyramide Drug Information

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