Disopyramide Side Effects

Common Side Effects

Disopyramide has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking the medication were carefully documented. As a result, it was possible to see what side effects occurred and how common they were.
 
In clinical studies, the most common disopyramide side effects included:
 
  • Dry mouth -- in up to 32 percent of people
  • Difficulty urinating -- up to 14 percent
  • Constipation -- up to 11 percent.
 
Other common reactions, occurring in 1 percent to 9 percent of people, included:
 
  • Blurred vision
  • Dry nose, eyes, or throat
  • An inability to empty the bladder completely when urinating (urinary retention)
  • Feeling the need to urinate frequently or urgently
  • Nausea
  • Abdominal (stomach) pain, bloating, or gas
  • Dizziness
  • Muscle weakness
  • Fatigue
  • Headache
  • General feelings of illness
  • General body aches and pains
  • Erectile dysfunction (impotence or ED)
  • Low blood pressure (hypotension)
  • Fluid retention causing body swelling (edema)
  • Weight gain
  • Shortness of breath
  • Chest pain
  • Fainting
  • Loss of appetite
  • Diarrhea
  • Vomiting
  • Rash
  • Itching
  • Nervousness
  • Worsening heart failure
  • New heart rhythm problems
  • Low blood potassium levels
  • Increased lipids (cholesterol).
 

Final Thoughts

You may experience some or none of the disopyramide side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking disopyramide or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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