Esmolol Dosage

Your healthcare provider will administer an appropriate dosage of esmolol for your situation based on the condition being treated, your weight, and various other factors. Typically, dosing for this medication starts with one or more "loading doses." After these doses (which are large, single doses given over 30 to 60 seconds each), a continuous infusion is started through an IV.

Esmolol Dosage: An Introduction

The dose of esmolol hydrochloride (Brevibloc®) that your healthcare provider recommends will vary depending on a number of factors, including:
  • The medical condition being treated
  • The urgency of the situation
  • Your weight
  • How you respond to the medication
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.

Esmolol Dosing Strategies

Ideally, a healthcare provider would have enough time to start with a low esmolol dosage and gradually adjust the dose until the desired results are achieved. However, since esmolol is often used in emergency situations, there may not be enough time for such a strategy.
Typically, dosing starts with one or more "loading doses." These are single, large doses given over 30 to 60 seconds each and are meant to rapidly control the heart rate (or blood pressure). Up to three loading doses may be given. After the loading doses, a continuous infusion (during which the medication is given at a constant rate by IV) is started.
If necessary, the esmolol continuous infusion may be continued for a day or two, at which time the patient should be switched to a different medication that is more appropriate for long-term use. When switching to a different medication, the dosage is usually reduced gradually in order to make sure that the new medication will adequately control the heart rhythm.
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Esmolol Drug Information

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