More Info on Drug Interactions With Lanoxin

Conivaptan
Conivaptan may increase Lanoxin blood levels, increasing your risk for serious side effects. Your healthcare provider may decide to monitor your Lanoxin levels with a simple blood test if you take these medications together, especially when you start or stop taking conivaptan.
 
Diuretics
Some diuretics decrease blood potassium levels. Taking any of these diuretics with Lanoxin increases your risk for Lanoxin toxicity. In addition, spironolactone may increase Lanoxin blood levels. Your healthcare provider may choose to monitor your potassium and Lanoxin levels with a simple blood test if you take Lanoxin with any of these diuretics.
 
Macrolide Antibiotics
Macrolide antibiotics may increase the amount of Lanoxin absorbed into the body, potentially increasing your risk for serious side effects. Older adults may have an increased risk for this interaction. Your healthcare provider may choose to monitor your Lanoxin levels with a simple blood test when you start and stop a macrolide antibiotic.
 
Metoclopramide
Metoclopramide may decrease the amount of Lanoxin absorbed into the body, potentially making it less effective. Your healthcare provider may want to monitor your Lanoxin levels with a simple blood test when you start or stop metoclopramide.
 
Midodrine
Combining midodrine with Lanoxin may increase your risk for an extremely low heart rate. Your healthcare provider may want to monitor your heart rate more closely if you take these medications together.
 
Milnacipran
There are reports of increased heart rate and low blood pressure when milnacipran was combined with Lanoxin. This interaction is likely only a concern when Lanoxin is given via intravenous (IV) injection.
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Lanoxin Drug Information

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