Additional Medicines That React With Lanoxin

Neomycin
Taking neomycin with Lanoxin may result in low blood levels of Lanoxin, potentially making the drug less effective. Your healthcare provider may choose to monitor your Lanoxin levels with a simple blood test when you first start and when you stop taking neomycin.
 
Neuromuscular-Blocking Medications
Combining Lanoxin with a neuromuscular-blocking agent may increase your risk for developing an abnormal heartbeat (heart arrhythmia). Your healthcare provider will closely monitor your heart if you take Lanoxin and need a neuromuscular-blocking drug. Make sure all your healthcare providers know you are taking Lanoxin.
 
Nonsteroidal Anti-Inflammatory drugs (NSAIDs)
Combining NSAIDs and Lanoxin may cause an increase in Lanoxin blood levels, potentially increasing the risk for serious side effects. Talk to your healthcare provider before taking these medicines together. Your healthcare provider may need to monitor your Lanoxin blood level.
 
P-glycoprotein (Pgp) Inducers
P-glycoprotein is a protein found in the body. One of its roles is to help remove substances, such as medications, out of the tissues so they can be excreted through the urine or feces. Pgp helps remove Lanoxin from the body, and medications known as Pgp inducers increase the activity of Pgp.
 
Taking Lanoxin with one of these Pgp inducers causes the drug to be removed from the body too quickly, potentially making it less effective. Your healthcare provider may choose to monitor your Lanoxin levels more closely if you take it with a Pgp inducer.
 
P-glycoprotein (Pgp) Inhibitors
P-glycoprotein is a protein found in the body. One of its roles is to help remove substances, such as medications, out of the tissues so they can be excreted through the urine or feces. Pgp helps remove Lanoxin from the body, and medications known as Pgp inhibitors decrease the activity of Pgp.
 
Taking Lanoxin with one of these drugs causes Lanoxin to be removed from the body more slowly, potentially increasing the amount of Lanoxin in your body and increasing your risk for serious side effects. Your healthcare provider may choose to monitor your Lanoxin levels if you take it with a Pgp inhibitor.
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