Amiodarone (Cordarone®, Pacerone®, Nexterone®) is generally a very effective medication for treating certain types of serious, irregular heartbeats known as ventricular arrhythmias. Although the typical results from amiodarone treatment tend to be positive, there are a number of factors that can affect this. Some of these factors include:
The type and severity of the arrhythmia being treated
Whether a person responds to and is able to tolerate the medication
Whether other antiarrhythmia medicines are being used.
Clinical trials have shown that up to 20 percent to 40 percent of people who tolerated and responded to amiodarone well enough to continue treatment for at least a year experienced a recurrence of their arrhythmia.
(Click Amiodarone for more information on typical results to expect from treatment with this antiarrhythmia medication. This article also covers details on how the drug works, potential side effects, and dosing instructions.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Amiodarone injection [package insert]. Lake Forest, IL: Bioniche Pharma USA, LLC.;2010 May.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed June 22, 2012.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed June 22 2012.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed June 22, 2012.
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