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When and How to Take Esmolol

Some general considerations include the following:
 
  • Esmolol comes in injectable form. It is given by IV.
     
  • Esmolol is usually used only temporarily. If long-term treatment is required, the patient should be switched to a different medication.
     
  • As with many IV medications, healthcare providers must take care to prevent the medication from leaking outside of a vein, as it can be very irritating and damaging to the tissues.
     
  • Healthcare providers must be very careful when making IVs with this medication. Deaths have resulted from inaccurately diluting the medication (usually from accidentally making the concentration too high).
     

Dosing Information

The dose of esmolol that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • The medical condition being treated
  • The urgency of the situation
  • Your weight
  • How you respond to the medication
  • Other medications you are taking
  • Other medical conditions you may have.
     
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Esmolol Dosage for more information.)
 

Esmolol Drug Interactions

Esmolol can potentially interact with a number of other medications (see Drug Interactions With Esmolol).
 

Overdose Information

An overdose of esmolol can cause cardiac arrest, dangerously low blood pressure (hypotension), a slow heart rate (bradycardia), and other serious problems. Massive overdoses (caused by inaccurate dilution of the medication) have caused deaths and permanent disability.
 
(Click Esmolol Overdose for more information.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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