Heart Home > Propafenone SR

People with an abnormal heart rhythm known as atrial fibrillation may benefit from taking propafenone SR. This prescription medication is approved to help prolong the time between symptoms in people with this heart problem. It comes as capsules that are taken twice daily, with about 12 hours between doses. Potential side effects include nausea, tiredness, and dizziness.

What Is Propafenone SR?

Propafenone SR (Rythmol SR®) is a prescription medication that belongs to a group of medicines known as antiarrhythmics. It is approved to prolong the symptom-free time (to delay recurrence) in certain people with an abnormal heart rhythm called atrial fibrillation (commonly referred to as "a-fib").
Propafenone SR is an extended-release medication. The active ingredient in propafenone SR is available in a regular-release version as well -- propafenone (Rythmol®) tablets. Regular propafenone is taken by mouth three times a day. The doses of propafenone SR and propafenone are not interchangeable. Therefore, if you switch from one medication to the other, you will need to take a different dose.
(Click What Is Propafenone SR Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, propafenone SR can cause side effects. However, not everyone who uses the drug will experience problems. Most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common propafenone SR side effects include but are not limited to:
  • Dizziness
  • A fast or irregular heartbeat
  • Taste changes
  • Nausea
  • Tiredness.
(Click Propafenone SR Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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