Heart Home > Drug Interactions With Ranolazine

Fluconazole, progesterone, and tamoxifen are just a few of the drugs known to interact with ranolazine. Reactions with this angina medication can cause a number of problems, such as decreasing the effectiveness of ranolazine or increasing your risk for serious side effects. Before starting ranolazine, let your healthcare provider know about all medications, vitamins, and supplements you are taking.

An Overview of Ranolazine Interactions

Ranolazine (Ranexa®) can potentially interact with a number of other medications. Some of the products that may interfere with ranolazine include but are not limited to:
 
  • CYP 3A4 inducer medications, such as:
 
 
  • Moderate CYP 3A4 inhibitor medications, such as:
 
 
  • Strong CYP 3A4 inhibitor medications, such as:
 
 
 
 
  • P-glycoprotein inhibitors, such as:
 
 
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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