Mexitil and Breastfeeding

According to a few reports, Mexitil (mexiletine) does pass through breast milk. Although there have been some cases of women taking this drug while nursing, no significant problems have been reported. The manufacturer recommends women not take Mexitil while breastfeeding; however, many experts believe the drug is safe to use while nursing.

Can Breastfeeding Women Take Mexitil?

Mexitil® (mexiletine) is a prescription medication used to treat certain life-threatening arrhythmias (abnormal heart rhythms). This medication passes through breast milk. The manufacturer recommends that women not breastfeed while taking Mexitil. However, other experts generally consider the medication safe for use in women who are nursing.
 

More Information About Mexitil and Breastfeeding

There have been a few cases describing the use of Mexitil in breastfeeding women. In these cases, the drug was shown to pass through breast milk. Based on the amount found in breast milk, however, it was estimated that a nursing infant would receive less than 2 percent of the mother's Mexitil dosage.
 
In addition, Mexitil did not appear to cause problems in the nursing infants. One infant was reported to stop feeding and lost weight; however, researchers believed the problem was not caused by the medicine.
 
Several experts, including the American Academy of Pediatrics (AAP), consider Mexitil compatible with breastfeeding, especially if a woman is taking less than 600 mg of the medication a day and the infant is at least two months old. Because information about Mexitil and breastfeeding is limited, it is probably best to carefully monitor an infant who receives only breast milk if the mother is taking this drug. If problems are suspected, Mexitil blood levels can be measured in the infant by using a simple blood test.
 
If your healthcare provider recommends Mexitil while you are breastfeeding, you should carefully monitor your child for any potential side effects. This may include but is not limited to:
 
  • Difficulty feeding
  • Weight loss
  • Vomiting
  • Shakiness (tremors)
  • Changes in sleep
  • Excessive crying.
 
Let your child's healthcare provider know if you notice any of these symptoms, or anything else that seems out of the ordinary for your child.
 
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