Mexitil Side Effects

Some people who use Mexitil may develop side effects during treatment. Clinical trials have shown that some of the most commonly reported problems include nausea, lightheadedness, and headaches. Because this drug can also cause potentially dangerous problems, it is important to know which side effects need to be reported to your healthcare provider right away.

An Introduction to Mexitil Side Effects

As with any medicine, Mexitil® (mexiletine) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
(This article covers many, but not all, of the possible side effects with Mexitil. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Mexitil

Mexitil has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were carefully documented and compared to those that occurred in a similar group of people taking a placebo (a "sugar pill" that does not contain any active ingredients) or another antiarrhythmia medication. As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo or the other medication.
In these studies, the most common Mexitil side effects included:
  • Gastrointestinal (GI) side effects, such as nausea, vomiting, heartburn, or indigestion -- in up to 39.6 percent of people
  • Lightheadedness or dizziness -- up to 26.4 percent
  • Shakiness (tremors) -- up to 13.2 percent
  • Nervousness -- up to 11.3 percent
  • Problems with coordination -- up to 9.7 percent
  • Feelings of a pounding or racing heart -- up to 7.5 percent
  • Chest pain (angina) -- up to 7.5 percent
  • Changes in sleep -- up to 7.5 percent
  • Headache -- up to 7.5 percent
  • Blurred vision -- up to 7.5 percent.
Other common reactions, occurring in 1.2 percent to 5.7 percent of people, included:
  • Shortness of breath
  • Weakness
  • Diarrhea
  • Rash
  • Body swelling
  • Constipation
  • Fatigue
  • Dry mouth
  • Numbness, pricking, or tingling sensations
  • Changes in appetite
  • Ringing of the ears
  • Confusion
  • Abdominal (stomach) pain or cramps
  • Joint pain
  • Depression
  • Difficulty speaking
  • Fever
  • Worsening arrhythmias.
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Mexitil Medication Information

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