Nitroglycerin Ointment Dosage

If you have coronary artery disease, a healthcare provider may prescribe nitroglycerin ointment to prevent episodes of chest pain. The standard starting dose is a half-inch of nitroglycerin ointment placed on the skin. This ointment is normally applied once in the morning and again six hours later. It is important that your body has at least a 10-hour break from this medicine each day.

An Introduction to Your Dosage of Nitroglycerin Ointment

The dose of nitroglycerin ointment (Nitro-Bid®) your healthcare provider recommends will vary, depending largely on how you respond to the medication. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
This article refers to the nitroglycerin skin ointment that is used to treat chest pain, not the nitroglycerin ointment that is used to treat anal fissures (see Nitroglycerin Anal Ointment for more information about this medication).

Nitroglycerin Ointment Dosing Guidelines for Angina

The standard starting dosage of nitroglycerin ointment for preventing chest pain (angina) is a half-inch of the ointment, approximately 7.5 mg of nitroglycerin, applied twice daily, with the first dose in the morning and the second dose six hours later.
If this dose is not effective at preventing chest pain, your healthcare provider can double the amount (and even double it a second time), if necessary. At these higher dosages, the drug is still used just twice a day.
As with all nitroglycerin products, it is important that your body gets a 10- to 12-hour break from the drug every day. Without this break, your body quickly becomes accustomed to the effects of nitroglycerin and the drug will become completely ineffective within 24 hours. If you use nitroglycerin ointment once in the morning and again six hours later, this will provide a sufficient break.
If you are using the foil packets instead of the tube, it is important to know that one packet is equivalent to one inch of the ointment from the tube.
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Nitroglycerin Ointment Information

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