Norpace Dosage

Available in the form of a capsule, Norpace is usually taken every six hours to help control serious heart rhythm problems. The Norpace dosage a healthcare provider prescribes will vary for each person, depending on his or her age, weight, and response to the medicine. This medicine can also be made into a liquid suspension for children or people who have difficulty swallowing the capsules.

An Introduction to Dosing With Norpace

The dosage of Norpace® (disopyramide) your healthcare provider recommends will vary, depending on a number of factors, including:
  • How you respond to the medication
  • Your weight
  • Your age
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Norpace Dosage in Adults?

Norpace dosages are highly individualized, based on each person's response, and will therefore vary from person to person. Most irregular heart rhythms can be controlled with doses between 400 mg and 800 mg a day (taken as divided doses every 6 hours). In general, your healthcare provider will start you on a dose and then adjust the amount, depending on how you respond to the drug and whether you experience side effects.
The recommended initial dosage of Norpace for treating ventricular arrhythmias in most adults is usually 150 mg every 6 hours (for a total of 600 mg a day). However, lower doses are recommended for certain people.
The recommended initial dosage for people who have weakened hearts due to heart disease is 100 mg every 6 or 8 hours. The usual recommended dosage for people who weigh less than 110 pounds, people with liver disease, and people with moderate kidney disease is 100 mg every 6 hours. It is recommended that people with severe kidney disease be given 100 mg every 8, 12, or 24 hours, depending on the severity of the kidney disease.
If your healthcare provider determines that your arrhythmia needs to be controlled very quickly, you may be given a larger initial dose (a loading dose) of 300 mg at the beginning of treatment, before you start taking your normal Norpace dosage. If the loading dose does not control your arrhythmia within six hours, your healthcare provider may recommend you take Norpace 200 mg (instead of the usual 150 mg dosage) every 6 hours as your maintenance dose. If this amount does not control your arrhythmia within two days, your healthcare provider may further increase your dosage, or recommend a different medication.
People with weak heart muscles due to an enlarged heart should generally not receive Norpace loading doses, as they could cause a significant drop in blood pressure or heart failure.
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Norpace Medication Information

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