Norpace Drug Interactions

Norpace Drug Interactions Explained

The following sections explain in detail the potentially negative reactions that can occur when Norpace is combined with any of the drugs listed above.
Anticholinergic Medications
Anticholinergic medications can cause side effects, such as constipation, dry eyes, dry mouth, blurred vision, and urinary difficulty. Norpace has anticholinergic properties, and combining it with anticholinergic medications may increase your risk for these side effects. If you take Norpace with an anticholinergic medication, let your healthcare provider know if you develop bothersome or persistent side effects.
Beta Blockers
Beta blockers work by slowing down the heart rate. Norpace can magnify this effect, which could cause your heart rate to become too low. Talk to your healthcare provider about this potential reaction if you take Norpace with a beta blocker medication.
Certain Other Antiarrhythmia Medications
In general, Norpace should not be used with certain other antiarrhythmia medications (Class IA or IC antiarrhythmics), except to treat life-threatening arrhythmias that have not responded to treatment with one medication alone. This is because the combination may weaken the heart's ability to contract, and increase the risk for heart rhythm problems.
CYP 3A4 Inducer Medications
The liver breaks down Norpace using enzymes known as CYP 3A4 enzymes, and medications known as CYP 3A4 inducers can increase the activity of these enzymes. Thus, combining Norpace with one of these drugs may decrease the level of Norpace in your bloodstream, possibly decreasing its effectiveness. If you take a CYP 3A4 inducer, your healthcare provider may choose to monitor your Norpace blood levels, and adjust your dose if needed.
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Norpace Medication Information

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