Norpace Drug Interactions

CYP 3A4 Inhibitor Medications
The liver breaks down Norpace using enzymes known as CYP 3A4 enzymes, and medications known as CYP 3A4 inhibitors can decrease the activity of these enzymes. Thus, combining Norpace with one of these drugs may increase the level of Norpace in your bloodstream, increasing your risk for side effects. Your healthcare provider may need to closely monitor you, and possibly adjust your dose, if you take Norpace with a CYP 3A4 inhibitor.
 
Dronabinol
Combining Norpace with dronabinol could cause an increased heart rate (tachycardia). Talk to your healthcare provider about this potential interaction before combining these medications.
 
QT-Prolonging Medications
Combining Norpace with any other medication that can cause QT prolongation (a certain change in the heart rhythm) may increase your risk of a life-threatening abnormal heartbeat (heart arrhythmia). Because of this risk, Norpace should generally not be taken with other QT-prolonging medications.
 
Medications Used to Treat Dementia
Norpace may decrease the effectiveness of medications used to treat dementia. If you are taking a medicine for dementia, make sure your healthcare provider knows you are also taking Norpace.
 
Nabilone
Combining Norpace with nabilone could cause an increased heart rate (tachycardia). Talk to your healthcare provider about this potential interaction before combining these medications.
 
Potassium Chloride
Norpace may increase the risk for stomach irritation from potassium chloride tablets or capsules. Liquid or effervescent (tablets that dissolve in water) forms of potassium may be safer options for people taking Norpace. Talk to your healthcare provider about this potential interaction if you take potassium chloride and Norpace.
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Norpace Medication Information

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