Pacerone Side Effects

Clinical studies have shown that 75 percent of people who take Pacerone will develop some type of reaction to this drug. Some of the most commonly reported Pacerone side effects include fatigue, constipation, and nausea. While many problems tend to be minor, there are serious side effects like chest pain or problems breathing that require immediate medical treatment.

An Introduction to Pacerone Side Effects

Just like any medicine, Pacerone® (amiodarone hydrochloride) can cause side effects. In fact, side effects are quite common with this medicine, occurring in about 75 percent of people in clinical trials. Fortunately, in many cases, reactions tend to be minor and either require no treatment or are treated easily by you or your healthcare provider.
If serious or intolerable side effects occur, your healthcare provider may reduce your dose or recommend you stop taking the medicine altogether. In clinical trials, up to 20 percent of people stopped taking Pacerone due to side effects.
(This article covers many, but not all, of the possible side effects with Pacerone. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Pacerone

The prescribing information for most prescription medications contains detailed information about side effects that occurred in clinical trials, including the exact percentage of people who experienced problems. However, the information for older medications, including Pacerone, is less precise. In the case of Pacerone, the prescribing information includes general (but not exact) percentages.
In clinical studies, the most common Pacerone side effects included:
  • Neurological side effects, which occurred in 20 percent to 40 percent of people and included:
    • General feelings of discomfort or illness
    • Fatigue
    • Tremors and other uncontrolled movements
    • Muscle weakness
    • Problems with coordination and walking
    • Numbness, tingling, and burning sensations in the hands, legs, or feet
  • Gastrointestinal (GI) side effects, which occurred in 10 percent to 33 percent of people and included:
  • Skin reactions, which occurred in about 15 percent of people and included problems like sensitivity to the sun.
Other common reactions, occurring in 1 percent to 9 percent of people, included:
  • Dizziness
  • Changes in vision
  • Increases in blood liver enzymes, which could be a sign of liver problems (found using a blood test)
  • Breathing problems
  • Thyroid problems (hyperthyroidism or hypothyroidism)
  • Decreased sex drive (decreased libido)
  • Insomnia
  • Headache
  • Sleep problems
  • Heart failure
  • A new arrhythmia
  • Abdominal (stomach) pain
  • Liver problems
  • Flushing (sudden warmth and redness of the face, neck, and upper chest)
  • Changes in the ability to taste or smell
  • Edema (swelling due to fluid retention)
  • Changes in the amount of saliva in your mouth
  • Abnormal bleeding or bruising.
Rare side effects, occurring in less than 1 percent of people, included:
It is important to know that Pacerone stays in the body for months after you stop taking it. Therefore, you may continue to experience adverse reactions even though you are no longer taking the medicine.
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Pacerone Medication Information

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