Answers to Questions on Pentoxifylline

Drug Interactions

Pentoxifylline can potentially interact with a few other medicines (see Drug Interactions With Pentoxifylline).

What If I Take an Overdose of Pentoxifylline?

People who take too much of this medication may experience low blood pressure (hypotension), a slowed heart rate, seizures, agitation, deep sleep, fever, or a serious condition called atrioventricular (AV) block. AV block is a disturbance of the regular rhythm of the heart.
If you happen to overdose on this medication, seek immediate medical attention.
(Click Trental Overdose for more information.)

What Should I Do If I Miss a Dose?

If you forget to take a dose of pentoxifylline, take it as soon as possible. If it is almost time for your next dose, skip your missed dose and continue with your regular dosing schedule. Do not take a double dose.

How Does This Medication Work?

Pentoxifylline increases the ability of white and red blood cells to change shape as they pass through narrow spaces such as blood vessels. The exact mechanism that allows this shape change is unknown. Pentoxifylline also helps the blood flow more freely, allowing more oxygen to reach the extremities.
Pentoxifylline comes in an extended-release (long-acting) tablet so that the medication works consistently from dose to dose. Do not crush or chew the tablet, as this reduces its ability to work reliably.
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Pentoxifylline Drug Information

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