Precautions and Warnings With Pentoxifylline

Before taking pentoxifylline, it's important to understand that this medication can cause problems for some people, such as an increased risk for bleeding problems, low blood pressure, or an irregular heart rhythm. Safety precautions to be aware of with pentoxifylline also include warnings of potential drug interactions and allergic reactions. Do not take this drug if you have previous bleeding in the brain or retina.

What Should I Tell My Healthcare Provider Before Taking Pentoxifylline?

You should talk with your healthcare provider prior to taking pentoxifylline (Trental®) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as liver failure, cirrhosis, or hepatitis
  • Previous bleeding in the brain or retina, or other bleeding complications
  • Low blood pressure (hypotension) or are taking blood pressure medications
  • Any allergies, including allergies to pentoxifylline, caffeine, theophylline, other medicines, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
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Pentoxifylline Drug Information

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