Potential Problems With Pentoxifylline

Common Side Effects

Pentoxifylline has been studied extensively in clinical trials. In these studies, one group of people received the real medication, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
 
In these studies, the most common side effects of pentoxifylline included but were not limited to:
 
  • Nausea -- up to 2.2 percent of people
  • Vomiting -- up to 1.2 percent.
     
Side effects involving the digestive and central nervous systems appear to be the most common when taking pentoxifylline. Nausea and vomiting appear to be reduced when this medication is taken with food.
 
If you experience nausea or vomiting, you should talk to your healthcare provider about lowering your dose of pentoxifylline. If the side effects continue after the dose is reduced, discuss with your healthcare provider whether the drug should be discontinued. Do not stop taking this drug or reduce the dosage without first consulting your healthcare provider.
 

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking pentoxifylline or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
 
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Pentoxifylline Drug Information

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