Side Effects of Pentoxifylline

While most people tolerate pentoxifylline well, it is still possible for side effects to occur. Common reactions to pentoxifylline include nausea and vomiting. In many cases, your healthcare provider can lower your dosage to help alleviate these problems. However, if you experience more serious reactions, such as chest pain, seizures, or difficulty breathing, contact your healthcare provider immediately.

An Introduction to Side Effects of Pentoxifylline

Just like any medicine, pentoxifylline (Trental®) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with pentoxifylline. Your healthcare provider can discuss a more complete list with you.)
 

Serious Pentoxifylline Side Effects

Some pentoxifylline side effects are potentially serious and should be reported immediately to your healthcare provider.
 These include but are not limited to:
 
  • Agitation
  • Chest pain
  • Fast or irregular heartbeat
  • Flushing
  • Seizures
  • Signs of an allergic reaction, such as:
     
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
 
Side Effects of Pentoxifylline Article Continues on Next Page >
Written by/reviewed by: Pamela Schoenen, PharmD candidate
Last reviewed by: Kristi Monson, PharmD
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