Pradaxa Overdose

The effects of a Pradaxa (dabigatran) overdose could include potentially dangerous bleeding problems, such as vomiting blood, internal bleeding, or bleeding in the brain. If you believe you have taken too much of this medication, seek immediate medical attention. Even if you have taken a normal dose of Pradaxa, contact your healthcare provider right away if you experience vision changes, a severe headache, or easy bruising.

Can You Take Too Much Pradaxa?

Pradaxa® (dabigatran etexilate mesylate) is a prescription anticoagulant ("blood thinner") medication used to prevent blood clots and strokes in people with atrial fibrillation (a certain type of irregular heart rhythm). An overdose with Pradaxa can be quite serious, as it can cause dangerous internal bleeding.
 

Effects of an Overdose

The most important effect of a Pradaxa overdose is bleeding. This can include obvious bleeding (such as vomiting of blood, nosebleeds, or bright-red blood in the stool) or bleeding that is less obvious (such as internal bleeding).
 
Signs and symptoms of a Pradaxa overdose might include:
 
  • Easy bruising
  • Cuts or scrapes that are slow to stop bleeding
  • Black, tarry stools, bright-red blood in the stool, or vomiting of blood (signs of gastrointestinal bleeding)
  • Signs of a hemorrhagic stroke (bleeding in the brain), such as vision or speech changes, weakness or numbness in an arm or leg, or a severe headache.
     

Treatment Options

If an overdose of Pradaxa (or even a normal dose) causes bleeding problems, a platelet or blood transfusion may be given to restore the blood's ability to clot.
 
 
Any other complications that arise will also be treated as necessary. Dialysis can be useful for rapidly removing Pradaxa from the bloodstream. Because this medication is excreted from the body in the urine, IV fluids and/or diuretics may be administered to help speed up this process.
 
It is important that you seek medical attention immediately if you believe that you or someone else may have overdosed on Pradaxa.
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
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