Ranolazine

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • A heart problem known as QT prolongation or long QT syndrome
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
 
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Ranolazine to learn more, including information on who should not take the drug.)
 

How Does It Work?

Unlike other angina medications, ranolazine does not affect the heart rate or blood pressure. It is uncertain exactly how ranolazine works at this time. It is known that the drug inhibits certain sodium currents in the heart, and this is probably responsible for the effects of ranolazine.
 

When and How to Take This Medicine

Some general considerations to keep in mind during treatment with this medication include the following:
 
  • Ranolazine comes in extended-release tablet form. It is taken by mouth twice a day, with about 12 hours between doses.
  • You may take this medication with or without food. If it seems to bother your stomach, try taking it with a little food.
  • Swallow the tablets whole; do not crush, break, chew, or dissolve them.
  • For the medication to work properly, it must be taken as prescribed.
 
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Ranolazine Drug Information

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