Ranolazine Side Effects

Common Side Effects

Ranolazine has been studied extensively in clinical trials. In these studies, one group of people received the real medication, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it is possible to see what ranolazine side effects occurred, how often they appeared, and how they compared to the group who took the placebo.
In these studies, the most common ranolazine side effects included:
  • Dizziness -- in up to 6.2 percent of people
  • Headache -- up to 5.5 percent
  • Constipation -- up to 4.5 percent
  • Nausea -- up to 4.4 percent.
Other common side effects, occurring in 0.5 percent to 2 percent of people, included but were not limited to:
  • A slow heart rate (bradycardia)
  • Feelings of a rapidly or forcefully beating heart (heart palpitations)
  • Ringing in the ears (tinnitus)
  • A spinning sensation (vertigo)
  • Abdominal (stomach) pain
  • Dry mouth
  • Vomiting
  • Swelling/water retention in the extremities
  • Shortness of breath
  • Low blood pressure (hypotension).

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking ranolazine or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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Ranolazine Drug Information

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