What Is Ranolazine Used For?

Ranolazine is prescribed to prevent angina (chest pain) in adults who have a chronic form of this condition. This drug is not approved for treating angina attacks that have already started. It is taken twice daily and does not affect heart rate or blood pressure, as other angina medications do. Ranolazine is approved for use in adults only.

An Overview of Uses for Ranolazine

Ranolazine (Ranexa®) is a prescription chronic angina (chest pain) medication. It is taken twice a day to help prevent angina attacks.

What Is Angina?

Angina is usually caused by coronary artery disease (also known as coronary heart disease), a condition in which the small blood vessels that supply blood to the heart become too narrow to adequately supply the heart with enough blood and oxygen.
Many of the treatments for chronic angina affect the heart rate and blood pressure, often causing dangerous or intolerable side effects. In addition, nitroglycerin medications, which are often used for angina treatment, typically cause headaches and cannot be used around-the-clock or else they become ineffective.
Ranolazine works differently than other angina medications and does not affect the heart rate or blood pressure. It stays effective when used around-the-clock and has a low risk for headaches.
However, ranolazine does not work quickly enough to stop an attack of angina that is already occurring. Instead, it is taken on a daily basis to help prevent angina attacks. In that sense, ranolazine is not appropriate for people that have only occasional or rare episodes of angina. Ranolazine can be taken in combination with any of the usual drugs taken to treat angina.

How Does This Medicine Work?

Unlike other angina medications, ranolazine does not affect the heart rate or blood pressure. It is uncertain exactly how ranolazine works at this time. It is known that the drug inhibits certain sodium currents in the heart, and this is probably responsible for the effects of ranolazine.
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Ranolazine Drug Information

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