Samsca Side Effects

Serious Side Effects

Some side effects of Samsca should be reported immediately to your healthcare provider. These potential reactions include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Signs of a serious condition known as osmotic demyelination syndrome, which can happen when sodium levels are increased too quickly, including:
    • Trouble speaking or swallowing
    • Problems controlling your muscles
    • Muscle weakness, especially in the arms and legs
    • Drowsiness
    • Confusion
    • Changes in mood
    • Seizures
  • Dizziness or fainting
  • Persistent vomiting or diarrhea, especially if you cannot keep down fluids
  • Stools that are bright red, maroon, black, or tarry
  • Vomiting blood or vomit that looks like coffee grounds
  • Signs of dehydration, such as:
    • Feeling very thirsty
    • Decreased urination
    • Dry mouth or skin.

Final Thoughts

You may experience some or none of the Samsca side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking Samsca or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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Samsca Medication Information

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