More Info on Sotalol Interactions

Digoxin
Combining sotalol with digoxin may cause a dangerously slow heart rate (bradycardia) or new or worsened arrhythmias. You may need to be monitored closely if you take these medications together. In some cases, sotalol and digoxin should not be combined.
 
Many Asthma or COPD Medications
As a beta blocker, sotalol may interfere with the effectiveness of many asthma or COPD medications. This is usually not an issue, since people with asthma or COPD should not take sotalol anyway (it may worsen breathing problems). In the rare case that a healthcare provider recommends that such medications be taken together, higher-than-normal doses of the asthma or COPD medications may be required.
 
Other Beta Blockers
Sotalol is a beta blocker and generally should not be combined with other beta blockers, as this may increase the risk of serious side effects.
 
QT-Prolonging Medications
Sotalol can cause a dangerous change in the heart rhythm known as QT prolongation. To help decrease the risk of this drug interaction, sotalol should not be combined with other medications that have this effect. Many different types of medications can cause this problem (see QT-Prolonging Medications for a list of such medications).
 
Reserpine
Combining reserpine with a beta blocker can increase the risk of serious side effects. You may need to be monitored closely if you take these medications together. In some cases, sotalol and reserpine should not be combined.
 

Final Thoughts on Drug Interactions With Sotalol

It is possible that not all sotalol interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 
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Sotalol Drug Information

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