Detailed Information on Sotalol Indications

Using Sotalol for Ventricular Arrhythmias
Sotalol is also approved for treating life-threatening ventricular arrhythmias. These are irregular heart rhythms that occur in the ventricles (the lower chambers of the heart). It is important to understand that antiarrhythmic medications like sotalol have not been shown to improve survival in people with ventricular arrhythmias and may sometimes actually cause them. This is why the medication is approved for treating only ventricular arrhythmias that are life-threatening. For cases that are not as serious, the risks outweigh the benefits.

How Does the Medication Work?

Sotalol belongs to two different classes of drugs; it is both a beta blocker and a Class III antiarrhythmic medication.
As a beta blocker, sotalol slows the heart rate and increases the amount of time that a certain area of the heart (the AV node) is not responsive to an electrical signal. This means that if an electrical signal comes too soon, which could happen with atrial fibrillation or atrial flutter, the signal will not pass on to the rest of the heart.
As a Class III antiarrhythmic medication, sotalol blocks potassium channels in the heart. This action helps to control an irregular heart rhythm.

Sotalol Use in Children

Sotalol is not approved for use in children, as there is not enough research to demonstrate that it is safe and effective for this age group. However, dosing recommendations for children are available, and sotalol may be used in children if necessary.

Is Sotalol Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this medication for something other than the uses discussed in this article. At this time, however, there are no universally accepted off-label uses for sotalol.
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Sotalol Drug Information

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