Possible Reactions to Ticagrelor

Bothersome or Easily Treated Side Effects

Some ticagrelor side effects are merely bothersome and/or are easily treated. In either case, they are not usually dangerous. These include but are not limited to:
  • Shortness of breath -- in up to 13.8 percent of people
  • Headache -- up to 6.5 percent
  • Cough -- up to 4.9 percent
  • Dizziness -- up to 4.5 percent
  • Nausea -- up to 4.3 percent.
It is important to understand that these "side effects" may not actually be related to ticagrelor and may not be true side effects at all. In studies, ticagrelor was compared to a similar medication (clopidogrel, also known as Plavix®), not to a placebo (a "sugar pill" with no active ingredients).
Studies that compare similar medications instead of using a placebo have trouble differentiating between true side effects and problems caused by unrelated factors, such as the disease itself. Also, both ticagrelor and Plavix were taken with aspirin, so some of the side effects may actually have been caused by aspirin.
Other somewhat common ticagrelor side effects (reported in 3 to 4.2 percent of people) included:
Again, it is likely that many of these so-called side effects are not true side effects at all. For instance, atrial fibrillation is most likely due to heart damage caused by the heart attack itself or other risk factors, not by the medication.
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Ticagrelor Drug Information

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