How Does Tikosyn Work?

Tikosyn® (dofetilide) is prescribed to treat certain types of an irregular heart rate, specifically atrial fibrillation (commonly referred to as "a-fib") or atrial flutter. This medicine can be used to get the heart back to a regular rhythm and to help maintain it. But how does Tikosyn work?
As a Class III antiarrhythmic medication, Tikosyn blocks potassium channels in the heart, preventing potassium from leaving the heart muscle cells. This action extends the period of time that heart cells will not respond to a new electrical signal.
If an electrical signal comes through too soon, it can prematurely activate the heart and cause a rapid heart rate. Tikosyn helps the heart resist any premature electrical signals by blocking potassium channels.
(For more details on how this medicine works, click Tikosyn. This resource takes a closer look at what this prescription drug is used for, potential side effects, and dosing instructions.)
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