Tikosyn Dosage

Tikosyn comes in the form of a capsule that is usually taken twice daily. The recommended Tikosyn dosage will depend on your heart rate, kidney function, and other medications you are taking, among other factors. You will receive your first doses in the hospital, where your heart rate and kidney function can be carefully monitored for at least three days.

An Introduction to Dosing With Tikosyn

The dose of Tikosyn® (dofetilide) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Your heart rate
  • Your kidney function
  • Other medical conditions you may have
  • Other medicines you are taking.
 
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 

What Is the Recommended Tikosyn Dosage?

The recommended initial Tikosyn dosage for treating atrial fibrillation or atrial flutter is usually between 125 mcg (0.125 mg) and 500 mcg (0.5 mg) twice a day, depending on how well your kidneys are functioning. You will be started on this dose in the hospital.
 
Two to three hours after you receive your first dose, your healthcare provider will monitor your heart rate and may reduce your Tikosyn dosage based on the results of this monitoring. He or she will continue to monitor your heart rate in the hospital for at least three days. Make sure to continue taking the dose your healthcare provider recommends after you leave the hospital.
 
Your healthcare provider will continue to monitor your kidneys and heart rate at least every three months. If your kidney function worsens, your healthcare provider may recommend you stop taking Tikosyn or take a lower dose. He or she may also recommend you stop taking Tikosyn if you develop an abnormal heartbeat.
 
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Tikosyn Drug Information

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