Tikosyn Drug Interactions

Fingolimod
Combining fingolimod with Tikosyn could increase your risk for a heart rhythm problem. Your healthcare provider will monitor your heart rhythm before starting fingolimod if you are taking Tikosyn.
 
Lidocaine
Combining lidocaine with Tikosyn could increase the risk for a potentially serious abnormal heartbeat. Talk to your healthcare provider before using lidocaine products, such as lidocaine cream or gel, if you are taking Tikosyn, as some of the lidocaine could be absorbed into the body and potentially interact with Tikosyn.
 
Loop Diuretics
Combining a loop diuretic with Tikosyn could increase your risk for a potentially serious heart rhythm problem. Your healthcare provider may need to monitor your heart rhythm more closely if you take these medicines together.
 
QT-Prolonging Medications
In general, Tikosyn should not be combined with any other medication that can cause QT prolongation (a certain change in the heart rhythm), due to the risk of a life-threatening abnormal heartbeat (heart arrhythmia).
 
Megestrol
Megestrol may increase blood levels of Tikosyn, increasing the risk for a dangerous heart rhythm problem. These medicines should not be used together.
 
Metformin
Metformin may increase blood levels of Tikosyn, potentially increasing the risk for Tikosyn side effects. Your healthcare provider may choose to monitor you more closely if you take these medicines together.
 
Mifepristone
Combining mifepristone with Tikosyn may increase your risk for a dangerous abnormal heartbeat. You should not take Tikosyn in combination with mifepristone, or within two weeks of taking it, if you have been using mifepristone on a continuous basis. It is unknown whether the use of a single dose of mifepristone to terminate a pregnancy will interact with Tikosyn in the same way.
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Tikosyn Drug Information

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