Tikosyn Drug Interactions

Prochlorperazine
Prochlorperazine may increase blood levels of Tikosyn, potentially increasing the risk for Tikosyn side effects, including potentially serious side effects. These medicines should not be used together.
 
Quinine
In general, you should not take quinine in combination with Tikosyn because of an increased risk for a life-threatening abnormal heartbeat (heart arrhythmia) if these medicines are used together.
 
Thiazide Diuretics
Combining Tikosyn with a thiazide diuretic can increase your risk for a potentially life-threatening abnormal heartbeat. The manufacturer of Tikosyn recommends it not be taken with hydrochlorothiazide. You should talk to your healthcare provider before taking Tikosyn with any of the thiazide diuretics listed above.
 
Toremifene
In general, you should not take toremifene in combination with Tikosyn because of an increased risk for a life-threatening heart rhythm problem if these medicines are used together.
 
Triamterene
Triamterene may increase blood levels of Tikosyn, potentially increasing the risk of Tikosyn side effects. Your healthcare provider may need to monitor you more closely if you take these drugs together. Tikosyn should not be used in combination with triamterene/HCTZ.
 
Trimethoprim
Trimethoprim increases the amount of Tikosyn in the blood, potentially increasing the risk for a dangerous heart rhythm problem. These medicines should not be taken together.
 
Verapamil
Verapamil increases blood levels of Tikosyn, increasing the risk for a dangerous heart rhythm problem. You should not take verapamil if you take Tikosyn.
 
Vemurafenib
Combining vemurafenib with Tikosyn can increase the risk of a dangerous abnormal heartbeat. Therefore, these medicines should not be used together.
 
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Tikosyn Drug Information

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